{"id":5683,"date":"2025-03-19T10:47:05","date_gmt":"2025-03-19T10:47:05","guid":{"rendered":"https:\/\/perseivivarium.com\/blog\/?p=5683"},"modified":"2025-03-19T10:47:05","modified_gmt":"2025-03-19T10:47:05","slug":"prevention-diagnosis-and-treatment-of-diseases-using-digital-biomarkers","status":"publish","type":"post","link":"https:\/\/perseivivarium.com\/blog\/prevention-diagnosis-and-treatment-of-diseases-using-digital-biomarkers\/","title":{"rendered":"Prevention, diagnosis, and treatment of diseases using Digital Biomarkers"},"content":{"rendered":"\n[et_pb_section fb_built=&#8221;1&#8243; theme_builder_area=&#8221;post_content&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221;][et_pb_row _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_column _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; type=&#8221;4_4&#8243; theme_builder_area=&#8221;post_content&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; theme_builder_area=&#8221;post_content&#8221; custom_margin=&#8221;-70px||||false|false&#8221; hover_enabled=&#8221;0&#8243; sticky_enabled=&#8221;0&#8243;]<h1><span class=\"NormalTextRun SCXW141994475 BCX0\">Prevention, diagnosis, and treatment of diseases using <\/span><span class=\"NormalTextRun SCXW141994475 BCX0\">D<\/span><span class=\"NormalTextRun SCXW141994475 BCX0\">igital <\/span><span class=\"NormalTextRun SCXW141994475 BCX0\">B<\/span><span class=\"NormalTextRun SCXW141994475 BCX0\">iomarkers<\/span><\/h1>\n<p><span class=\"NormalTextRun SCXW141994475 BCX0\">by Pedro Vergara, March 19, 2025<\/span><\/p>[\/et_pb_text][et_pb_image src=&#8221;https:\/\/perseivivarium.com\/blog\/wp-content\/uploads\/2025\/03\/Prevention-diagnosis-and-treatment-of-diseases-using-Digital-Biomarkers.jpg&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; theme_builder_area=&#8221;post_content&#8221; hover_enabled=&#8221;0&#8243; sticky_enabled=&#8221;0&#8243; title_text=&#8221;Prevention, diagnosis, and treatment of diseases using Digital Biomarkers&#8221;][\/et_pb_image][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; theme_builder_area=&#8221;post_content&#8221; hover_enabled=&#8221;0&#8243; sticky_enabled=&#8221;0&#8243;]<p><span data-contrast=\"auto\">Widespread digitalization, and the development and application of Artificial Intelligence (AI) in healthcare are enabling the <\/span><b><span data-contrast=\"auto\">implementation of ever more sophisticated tools in the diagnosis and treatment of, and research into, diseases, as is the case with Digital Biomarkers.<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/perseivivarium.com\/blog\/what-are-digital-biomarkers-and-what-benefits-do-they-provide-in-the-study-and-management-of-diseases\/\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">Digital Biomarkers are objective and quantifiable biological measurements that are obtained using digital technologies<\/span><\/a><span data-contrast=\"auto\"> like <\/span><b><span data-contrast=\"auto\">smartphones, wearables, sensors, and other devices that enable the collection of patient information in a simple way, without effort on the part of the patient, and outside of the hospital environment.<\/span><\/b><span data-contrast=\"auto\"> These data complement the patient\u2019s clinical information obtained from tests and medical visits, providing a broader view of his or her status and disease.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">As noted in the publication, <\/span><a href=\"https:\/\/www.nature.com\/articles\/s41746-024-01023-w\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">\u201cWalk, talk, think, see and feel: harnessing the power of digital biomarkers in healthcare\u201d<\/span><\/a><span data-contrast=\"auto\">, Digital Biomarkers from various sources can provide the following information:<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li><b><span data-contrast=\"auto\">Physical functioning:<\/span><\/b> <b><span data-contrast=\"auto\">The way in which we walk<\/span><\/b><span data-contrast=\"auto\"> provides a lot of information, and can be an <\/span><b><span data-contrast=\"auto\">indicator of various medical conditions.<\/span><\/b><span data-contrast=\"auto\">\u00a0These data can be obtained from <\/span><b><span data-contrast=\"auto\">wearables and some types of sensors.<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/li>\n<li><b><span data-contrast=\"auto\">Voice and speech:<\/span><\/b><span data-contrast=\"auto\">\u00a0<\/span><b><span data-contrast=\"auto\">Tone, timbre, and velocity<\/span><\/b><span data-contrast=\"auto\"> can be used to assess <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11560146\/pdf\/dib-2024-0008-0001-541456.pdf\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">physical state (like respiratory function and neuromuscular changes), emotional state, and the cognitive functioning of the person<\/span><\/a><span data-contrast=\"auto\">.\u00a0This information can be gathered from <\/span><b><span data-contrast=\"auto\">smartphones,<\/span><\/b><span data-contrast=\"auto\"> which <\/span><a href=\"https:\/\/wearesocial.com\/es\/blog\/2025\/02\/digital-2025-la-guia-esencial-del-estado-global-de-lo-digital\/\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">97.8% of the population uses today<\/span><\/a><span data-contrast=\"auto\">, so voice and speech become an <\/span><b><span data-contrast=\"auto\">easily collected and accessed Digital Biomarker for most patients.<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/li>\n<li><b><span data-contrast=\"auto\">Cognitive functioning:<\/span><\/b><span data-contrast=\"auto\">\u00a0This information is obtained from the i<\/span><b><span data-contrast=\"auto\">nteraction between the person and technological equipment<\/span><\/b><span data-contrast=\"auto\">, and is <\/span><b><span data-contrast=\"auto\">useful for neurological evaluation of the patient.<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/li>\n<li><b><span data-contrast=\"auto\">Visual: <\/span><\/b><span data-contrast=\"auto\">Using a <\/span><b><span data-contrast=\"auto\">camera, information can be collected about ocular movement, gaze, fixation, and visual attention<\/span><\/b><span data-contrast=\"auto\">, which can help in the <\/span><b><span data-contrast=\"auto\">diagnosis and monitoring of certain conditions and diseases.<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/li>\n<li><b><span data-contrast=\"auto\">Symptoms and mood:<\/span><\/b><span data-contrast=\"auto\">\u00a0Information can be obtained about<\/span><b><span data-contrast=\"auto\"> health status and emotional state of a person<\/span><\/b> <b><span data-contrast=\"auto\">using wearables that monitor cardiac frequency, skin conductivity, or body temperature, etc.<\/span><\/b><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><span data-contrast=\"auto\">In this way, the collection and inclusion of these markers in the management of diseases enables the compilation of a more complete and objective view of the general status of the patient and the progression of his or her disease, <\/span><b><span data-contrast=\"auto\">offering numerous benefits and significant potential for healthcare professionals and patients.<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><b><span data-contrast=\"auto\">Digital Biomarkers provide supportive information for the prevention and diagnosis of diseases<\/span><\/b><span data-contrast=\"auto\">, helping healthcare professionals to <\/span><b><span data-contrast=\"auto\">identify potential cases and respond more quickly to people with a higher risk of developing a disease.<\/span><\/b><span data-contrast=\"auto\"> In addition, through remote monitoring of patients, <\/span><b><span data-contrast=\"auto\">providers are aware of the patient\u2019s situation in real time, enabling intervention when necessary, as well as the adaptation of treatment<\/span><\/b><span data-contrast=\"auto\"> as a result of the collected data.\u00a0 As a result, this <\/span><b><span data-contrast=\"auto\">reduces the number of unnecessary hospital visits.<\/span><\/b><span data-contrast=\"auto\">\u00a0Finally, <\/span><b><span data-contrast=\"auto\">their use in clinical trials supports the development of decentralized clinical trials, <\/span><\/b><a href=\"https:\/\/www2.deloitte.com\/us\/en\/insights\/industry\/life-sciences\/digital-measurement-and-digital-biomarkers-are-the-future-of-healthcare.html\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">the collection of more exact and patient-centered metrics<\/span><\/a>, and <a href=\"https:\/\/www.capgemini.com\/wp-content\/uploads\/2024\/10\/The-opportunity-of-Digital-Biomarkers.pdf\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">reduces the costs associated with the clinical trial.<\/span><\/a><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">As we have seen, the use of Digital Biomarkers through Digital Health platforms offers a lot of potential, as this enables <\/span><b><span data-contrast=\"auto\">continuous monitoring of the patient\u2019s health status in a simple way <\/span><\/b><span data-contrast=\"auto\">and, often, <\/span><b><span data-contrast=\"auto\">without having to request a specific action by the patient.<\/span><\/b><span data-contrast=\"auto\">\u00a0<\/span><b><span data-contrast=\"auto\">This helps the provider to make diagnoses in a timely way, and detect complications quickly, acting at the appropriate time and improving the patient\u2019s health and quality of life.<\/span><\/b><span data-contrast=\"auto\">\u00a0This is only the beginning, as the application of these markers in the healthcare environment <\/span><b><span data-contrast=\"auto\">through technology and AI can create new ways to understand and treat diseases, promoting medical care that is more personalized and patient centered.<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;20px|0px|0px|0px&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;]<h4>Share<\/h4>\r[\/et_pb_text][et_pb_code _builder_version=&#8221;4.16&#8243; link_option_url_new_window=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][\/et_pb_code][et_pb_team_member name=&#8221;Pedro Vergara&#8221; position=&#8221;Business Development&#8221; image_url=&#8221;https:\/\/perseivivarium.com\/blog\/wp-content\/uploads\/2024\/09\/Pedro-Vergara-1-scaled.jpg&#8221; _builder_version=&#8221;4.27.4&#8243; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221; title_text=&#8221;Pedro Vergara&#8221; link_option_url=&#8221;https:\/\/www.linkedin.com\/in\/pedrovergarav\/&#8221; link_option_url_new_window=&#8221;on&#8221; sticky_enabled=&#8221;0&#8243;]<p>Persei vivarium<\/p>[\/et_pb_team_member][\/et_pb_column][\/et_pb_row][\/et_pb_section]\n","protected":false},"excerpt":{"rendered":"<p>Widespread digitalization, and the development and application of Artificial Intelligence (AI) in healthcare are enabling the implementation of ever more sophisticated tools in the diagnosis and treatment of, and research into, diseases, as is the case with Digital Biomarkers.<\/p>\n","protected":false},"author":2,"featured_media":5690,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[159],"tags":[286,11,256,257,226,305],"class_list":["post-5683","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-insights","tag-digital-biomarkers","tag-digital-health","tag-digital-therapeutics","tag-dtx","tag-salud-digital","tag-terapias-digitales"],"_links":{"self":[{"href":"https:\/\/perseivivarium.com\/blog\/wp-json\/wp\/v2\/posts\/5683","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/perseivivarium.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/perseivivarium.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/perseivivarium.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/perseivivarium.com\/blog\/wp-json\/wp\/v2\/comments?post=5683"}],"version-history":[{"count":9,"href":"https:\/\/perseivivarium.com\/blog\/wp-json\/wp\/v2\/posts\/5683\/revisions"}],"predecessor-version":[{"id":5695,"href":"https:\/\/perseivivarium.com\/blog\/wp-json\/wp\/v2\/posts\/5683\/revisions\/5695"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/perseivivarium.com\/blog\/wp-json\/wp\/v2\/media\/5690"}],"wp:attachment":[{"href":"https:\/\/perseivivarium.com\/blog\/wp-json\/wp\/v2\/media?parent=5683"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/perseivivarium.com\/blog\/wp-json\/wp\/v2\/categories?post=5683"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/perseivivarium.com\/blog\/wp-json\/wp\/v2\/tags?post=5683"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}