{"id":5626,"date":"2025-02-05T10:56:20","date_gmt":"2025-02-05T10:56:20","guid":{"rendered":"https:\/\/perseivivarium.com\/blog\/?p=5626"},"modified":"2025-02-05T11:09:28","modified_gmt":"2025-02-05T11:09:28","slug":"decentralized-clinical-trials-in-oncology-what-benefits-do-they-provide","status":"publish","type":"post","link":"https:\/\/perseivivarium.com\/blog\/decentralized-clinical-trials-in-oncology-what-benefits-do-they-provide\/","title":{"rendered":"Decentralized Clinical Trials in Oncology: What benefits do they provide?"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;-70px||||false|false&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<h1><span data-contrast=\"auto\" xml:lang=\"EN-US\" lang=\"EN-US\" class=\"TextRun SCXW212649931 BCX0\"><span class=\"NormalTextRun SCXW212649931 BCX0\">Decentralized <\/span><span class=\"NormalTextRun SCXW212649931 BCX0\">C<\/span><span class=\"NormalTextRun SCXW212649931 BCX0\">linical <\/span><span class=\"NormalTextRun SCXW212649931 BCX0\">T<\/span><span class=\"NormalTextRun SCXW212649931 BCX0\">rials in <\/span><span class=\"NormalTextRun SCXW212649931 BCX0\">O<\/span><span class=\"NormalTextRun SCXW212649931 BCX0\">ncology: What benefits do they provide?<\/span><\/span><\/h1>\n<p><span class=\"EOP SCXW212649931 BCX0\" data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335551550&quot;:2,&quot;335551620&quot;:2,&quot;335559738&quot;:0,&quot;335559739&quot;:0}\">by Pedro Vergara, February 5, 2025<\/span><\/p>\n<p>[\/et_pb_text][et_pb_image src=&#8221;https:\/\/perseivivarium.com\/blog\/wp-content\/uploads\/2025\/02\/Decentralized-Clinical-Trials-in-Oncology-What-benefits-do-they-provide.jpg&#8221; title_text=&#8221;Decentralized Clinical Trials in Oncology &#8211; What benefits do they provide&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><span data-contrast=\"auto\">Clinical research is one of the fundamental pillars of medicine that enables us to better understand diseases and to develop safe and effective therapies for their treatment, among other benefits.\u00a0Innovation and technology are providing high value in this area of development, enabling an evolution toward <\/span><b><span data-contrast=\"auto\">more sophisticated and efficient models, with which we are able to obtain high quality clinical evidence<\/span><\/b><span data-contrast=\"auto\">. This is the case with <\/span><b><span data-contrast=\"auto\">Decentralized Clinical Trials (DCT<\/span><\/b><span data-contrast=\"auto\">).<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:0,&quot;335559739&quot;:160}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Decentralized Clinical Trials are differentiated from traditional ones in that the <\/span><a href=\"https:\/\/perseivivarium.com\/blog\/what-is-a-decentralized-clinical-trial-and-what-advantages-does-it-offer\/\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">patients can participate without having to be present in person at the hospital or research institution<\/span><\/a><span data-contrast=\"auto\">.\u00a0In this case, the <\/span><b><span data-contrast=\"auto\">monitoring throughout the trial, as well as the necessary testing, is carried out remotely<\/span><\/b><span data-contrast=\"auto\">, and the data are gathered through a series of questionnaires to which the <\/span><b><span data-contrast=\"auto\">patient responds and\/or through connected devices.<\/span><\/b><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:0,&quot;335559739&quot;:0}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">In this context, technology and <\/span><b><span data-contrast=\"auto\">Digital Health platforms<\/span><\/b><span data-contrast=\"auto\"> play a key role, as they can be used as tools for the development and capture of information, thanks to their ability to <\/span><b><span data-contrast=\"auto\">collect data in real time (those reported by the patient as well as data from sensors and wearables), and to monitor the patient remotely.<\/span><\/b><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:0,&quot;335559739&quot;:0}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">As we previously saw in our article <\/span><a href=\"https:\/\/www.pmfarma.com\/articulos\/3546-quy-es-un-estudio-clynico-descentralizado-y-quy-ventajas-ofrece.html\" target=\"_blank\" rel=\"noopener\"><i><span data-contrast=\"none\">\u201c\u00bfQu\u00e9 es un Estudio Cl\u00ednico Descentralizado y qu\u00e9 ventajas ofrece?\u201d<\/span><\/i><\/a><span data-contrast=\"auto\">, <\/span><b><span data-contrast=\"auto\">DCTs offer a variety of advantages and benefits:<\/span><\/b><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:0,&quot;335559739&quot;:0}\">\u00a0<\/span><\/p>\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li><a href=\"https:\/\/www.farmaindustria.es\/web\/otra-noticia\/es-fundamental-trabajar-en-ensayos-clinicos-descentralizados-por-el-bien-de-los-pacientes-espanoles-independientemente-de-donde-vivan\/\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">They enable the researcher to recruit more patients and to generate a more heterogeneous sample, which improve the quality of the trial.<\/span><\/a><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559685&quot;:720,&quot;335559737&quot;:0,&quot;335559738&quot;:0,&quot;335559739&quot;:0,&quot;335559991&quot;:360}\"> <\/span><\/li>\n<li><b><span data-contrast=\"auto\">They increase patient retention<\/span><\/b><span data-contrast=\"auto\">, at a level <\/span><a href=\"https:\/\/isanidad.com\/279622\/descentralizacion-de-los-ensayos-clinicos-una-oportunidad-para-espana\/\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">95% higher than in traditional clinical trials<\/span><\/a><span data-contrast=\"auto\">, according to recent data.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559685&quot;:720,&quot;335559737&quot;:0,&quot;335559738&quot;:0,&quot;335559739&quot;:0,&quot;335559991&quot;:360}\">\u00a0<\/span><\/li>\n<li><span data-contrast=\"auto\">They improve accessibility for patients by avoiding unnecessary travel.\u00a0Data shows that almost <\/span><a href=\"https:\/\/isanidad.com\/279622\/descentralizacion-de-los-ensayos-clinicos-una-oportunidad-para-espana\/\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">70% of potential participants live more than two hours away from the research center<\/span><\/a><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559685&quot;:720,&quot;335559737&quot;:0,&quot;335559738&quot;:0,&quot;335559739&quot;:0,&quot;335559991&quot;:360}\">\u00a0<\/span><\/li>\n<li><span data-contrast=\"auto\">They enable remote monitoring of the patient.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559685&quot;:720,&quot;335559737&quot;:0,&quot;335559738&quot;:0,&quot;335559739&quot;:0,&quot;335559991&quot;:360}\"> <\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>This is contributing to the <b><span data-contrast=\"auto\">increase in the use of digital tools in clinical trials<\/span><\/b><span data-contrast=\"auto\">, which was encouraged in the recent publication of the <\/span><a href=\"https:\/\/www.aemps.gob.es\/informa\/la-aemps-publica-la-guia-para-la-realizacion-de-elementos-descentralizados-en-ensayos-clinicos\/\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">\u201cGu\u00eda para la realizaci\u00f3n de elementos descentralizados en ensayos cl\u00ednicos\u201d de la AEMPS<\/span><\/a><span data-contrast=\"none\">\u201d<\/span><span data-contrast=\"auto\">, published by the Spanish Agency of Medicines and Medical Devices.\u00a0<\/span><b><span data-contrast=\"auto\">The goal is to implement these trials, ensuring their appropriate operation.<\/span><\/b><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:0,&quot;335559739&quot;:0}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">If we focus on <\/span><b><span data-contrast=\"none\">research in oncology, Decentralized Clinical Trials offer significant potential<\/span><\/b><span data-contrast=\"none\"> as, in addition to <\/span><b><span data-contrast=\"none\">boosting access for oncology patients<\/span><\/b><span data-contrast=\"none\"> who otherwise <\/span><b><span data-contrast=\"none\">would not be able to benefit from them, they facilitate continuous remote monitoring, assuring the supervision that is needed in this disease<\/span><\/b><span data-contrast=\"none\">. Furthermore, because results and evidence are obtained without the need for the patient to be present in the medical center, <\/span><b><span data-contrast=\"none\">unnecessary travel and exposure are avoided<\/span><\/b><span data-contrast=\"none\">, as well as waiting time.\u00a0 This, in turn<\/span><b><span data-contrast=\"none\">, reduces costs (in time and money) for the patients and their family members, and improves their quality of life<\/span><\/b><span data-contrast=\"none\">, a very important aspect of this disease.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:0,&quot;335559739&quot;:160}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Additionally, thanks to how data are collected from these studies, <\/span><b><span data-contrast=\"auto\">the disease can be understood outside of the hospital environment, providing valuable information about how patients and their families behave during the time between hospital visits<\/span><\/b><span data-contrast=\"auto\">.\u00a0In a disease like cancer, where the adverse effects can appear days after the application of treatment, the ability of DCTs to <\/span><b><span data-contrast=\"auto\">capture these events with precision, and reduce the probability of loss of data, enables the trials to generate robust, quality data.<\/span><\/b><span data-contrast=\"auto\">\u00a0Thanks to this kind of clinical trial and the collection of data throughout the cycle and not only during patient visits, <\/span><b><span data-contrast=\"auto\">the management of the disease is improved, as there is a more complete patient-centered view.<\/span><\/b><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:0,&quot;335559739&quot;:0}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">As we have seen, the <\/span><b><span data-contrast=\"auto\">use of technology favors the implementation of Decentralized Clinical Trials, and allows for a more complete view of the patient<\/span><\/b><span data-contrast=\"auto\">, breaking down some obstacles that are found in traditional clinical trials.\u00a0This encourages the implementation of a greater number of these trials which, in their turn, will <\/span><b><span data-contrast=\"auto\">provide access to a greater number of patients, obtaining robust clinical evidence in an optimized way<\/span><\/b><span data-contrast=\"auto\">.\u00a0With the growing use of technology in healthcare, and the innovations that are arriving on the scene, we can say that the implementation of this type of trial will increase, becoming part of medicine now and in the future.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335559738&quot;:0,&quot;335559739&quot;:0}\">\u00a0<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;20px|0px|0px|0px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h4>Share<\/h4>\n<p>[\/et_pb_text][et_pb_code _builder_version=&#8221;4.16&#8243; link_option_url_new_window=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_code][et_pb_team_member name=&#8221;Pedro Vergara&#8221; position=&#8221;Business Development&#8221; image_url=&#8221;https:\/\/perseivivarium.com\/blog\/wp-content\/uploads\/2024\/09\/Pedro-Vergara-1-scaled.jpg&#8221; _builder_version=&#8221;4.27.4&#8243; link_option_url=&#8221;https:\/\/www.linkedin.com\/in\/pedrovergarav\/&#8221; link_option_url_new_window=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Persei vivarium<\/p>\n<p>[\/et_pb_team_member][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Clinical research is one of the fundamental pillars of medicine that enables us to better understand diseases and to develop safe and effective therapies for their treatment. Innovation and technology are providing high value in this area of development, enabling an evolution toward more sophisticated and efficient models.<\/p>\n","protected":false},"author":2,"featured_media":5634,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[159],"tags":[249,349,348,11],"class_list":["post-5626","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-insights","tag-clinical-trials","tag-dct","tag-decentralized-clinical-trial","tag-digital-health"],"_links":{"self":[{"href":"https:\/\/perseivivarium.com\/blog\/wp-json\/wp\/v2\/posts\/5626","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/perseivivarium.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/perseivivarium.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/perseivivarium.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/perseivivarium.com\/blog\/wp-json\/wp\/v2\/comments?post=5626"}],"version-history":[{"count":10,"href":"https:\/\/perseivivarium.com\/blog\/wp-json\/wp\/v2\/posts\/5626\/revisions"}],"predecessor-version":[{"id":5640,"href":"https:\/\/perseivivarium.com\/blog\/wp-json\/wp\/v2\/posts\/5626\/revisions\/5640"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/perseivivarium.com\/blog\/wp-json\/wp\/v2\/media\/5634"}],"wp:attachment":[{"href":"https:\/\/perseivivarium.com\/blog\/wp-json\/wp\/v2\/media?parent=5626"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/perseivivarium.com\/blog\/wp-json\/wp\/v2\/categories?post=5626"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/perseivivarium.com\/blog\/wp-json\/wp\/v2\/tags?post=5626"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}